Berenice was born in Rome to Agrippa and Cyprus before Agrippa became king in 36 C.E. She bore the Roman name of Julia.
She was Herods’ great-great-granddaughter and only thirteen years of age at the time she married Marcus, the son of Alexander, Head of the Jewish Community in Alexandria, and nephew of Philo the philosopher.
With the death of Marcus in 44 C.E, Berenice became a widow at only sixteen. She then married Herod -her father’s oldest brother- and became Queen of Chalcis, a tiny principality in the Lebanon Mountains. She would retain this title even after her husband’s death.
Berenice had two sons by Herod: Hyrcanus and Berenicianus. She was widowed for a second time in 48 C.E, being only twenty years of age.
After Herod’s death, the Kingdom of Chalcis was given to Berenice’s older brother, Agrippa II. Together with his brother and sister, he moved into the new Kingdom’s Residence into close quarters.
Many sources indicate that Agrippa II and Berenice were often found together in official capacities. They would appear in public together, as when Agrippa gave his peace address to the people of Jerusalem just before the outbreak of the revolt against Rome.
The New Testament mentions Berenice’s presence with her brother at Paul’s trial, and in rabbinic literature, she is mentioned as the Queen alongside her brother, the King. In two sources this constant companionship is interpreted as incest.
Josephus claimed that rumors of the siblings’ inappropriate relationship led Berenice to seek a third match.She decided to marry Polemo, King of Cilicia, who had to be circumcised and undertake a Jewish lifestyle. However, this was not a successful marriage. She, later on, left Polemo and returned to her kingdom.
Berenice was present in Palestine during the outbreak of the Jewish revolt against the Romans between 66–70 C.E. Josephus Flavius described her as a solitary peacemaker, using all her strength in that difficult period of the preliminaries of the revolt. She had made a vow to be in Jerusalem at that time.As required by the vow, her hair was shorn and she walked barefoot.
She made her way to the Roman governor’s palace to ask Gessius Florus and demanded to desist from the violent activities he had undertaken against the Jewish population of Jerusalem. But her efforts were to no avail.
She finally joint venture with her brother to still the Jewish insurrection.
It was during this time that Berenice met Titus and fell in love. He was eleven years her junior.
After the revolt, Titus returned to Rome to assist his father in the government, while Berenice stayed behind in Judea. They would be reunited after four years when she and Agrippa came to Rome in 75.
She lived with Titus at the palace and reportedly acted as his wife in every aspect. This was the time she was at the height of her power and quite influential during this period.
However, being under public pressure, Titus had to restore his reputation for his people and sent her away. When he became Emperor in 79, Berenice returned to Rome but she was not welcome anymore. Titus died two years later.
Berenice was to be remembered as a ”little Cleopatra” in her aspiration to become the Empress of Rome.